Research institute

THOR Research Institute

The THOR Research Institute (TRI) is a virtual entity that is comprised of investigators that span the translational research pipeline from basic science to clinical trials to implementation science. The TRI is eligible to submit funding applications for federal funding in the US. The TRI collaborates with academia, industry, and federal agencies to perform research in the area of resuscitation science.

The TRI also collaborates with industry to support licensure applications for devices and biologics in addition to educational programs.

Previous and current TRI projects include:

Development of a clinical trial to examine the safety and efficacy of cold stored platelets in patients with leukemia and thrombocytopenia.
Development of evidence-based recommendations for the treatment of females of childbearing potential with severe bleeding and the prevention/treatment of alloimmunization to reduce the risk of hemolytic disease of the fetus and newborn.
Comparing the hemostatic effect of multiple sources of fibrinogen in in vitro models of hemostasis.
Development of an online calculator that determines the hemostatic content of different blood products.
Designing studies to determine the efficacy and safety of a blood and IV warming system for use in the prehospital and in-hospital setting.
Establishment of a series of focus groups to educate clinicians on emerging therapies in transfusion medicine.

RESEARCH INSTITUTE DIRECTORS

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Philip C. Spinella, MD, FCCM

Professor, Department of Surgery and Department of Critical Care Medicine
University of Pittsburgh
Pittsburgh, PA USA

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Philip C. Spinella, MD, FCCM

Professor, Department of Surgery and Department of Critical Care Medicine
University of Pittsburgh
Pittsburgh, PA USA

Dr. Philip C. Spinella is the Director of the Pediatric Critical Care Translational Research Program at St Louis Children’s Hospital and a Professor of Pediatrics at Washington University School of Medicine. He is internationally recognized as an expert in transfusion medicine and the resuscitation of hemorrhagic shock. Dr. Spinella served 15 years in the US Army and separated as a Lieutenant Colonel in 2007. He is a veteran of the Iraq War, where he received a Bronze Star and the Combat Medic Badge for providing care under fire. In collaboration with investigators at the US Army Institute of Surgical Research, his groundbreaking work in the area of the treatment of hemorrhagic shock received the US Army’s Best Invention Award in 2008 for his role in the development of the concept of “damage control resuscitation”.

Dr. Spinella is a well-established clinical trialist, who has been funded by the US Department of Defense and the National Institutes of Health. He has published over 350 manuscripts and 21 chapters and is the editor for a textbook on the topic of trauma resuscitation. Dr. Spinella has also participated in, organized research symposia for, or provided external review of research programs for the FDA, NIH, DoD, Homeland Security, and the Department of Health and Human Services. He has also participated on a committee for the National Academy of Sciences to develop recommendations for a national trauma system in the US. Dr. Spinella co-founded the THOR Network and has been its Co-Director since 2010.

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Andrew P. Cap, MD, PhD

Colonel, U.S. Army, Retired
Professor of Medicine
Uniformed Services University
USA

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Andrew P. Cap, MD, PhD

Colonel, U.S. Army, Retired
Professor of Medicine
Uniformed Services University
USA

Andrew (Andre) Cap, MD, PhD, is an internationally respected clinician-scientist in the field of trauma and critical care hematology with over 315 peer-reviewed articles and over 12,800 citations (h-index 60). Colonel Cap recently retired from the U.S. Army Medical Corps, where he served as Director of Research, U.S. Army Institute of Surgical Research (USAISR). In that capacity, he managed over 350 personnel and a budget of over $55M in executing the DoD’s primary intramural research program in combat casualty care.

Prior to this role, he led the U.S. Army’s Blood Research Program, and served as the Brooke Army Medical Center Program Director, Clinical Research Fellowship, and Associate Director, Hematology and Medical Oncology Fellowship. He also served as Chief of Medicine, 47th Combat Support Hospital, and as CENTCOM Theater Hematology Consultant.

He has worked extensively with the Armed Services Blood Program, Special Operations Command and Joint Trauma System (JTS) on a variety of blood and combat casualty care challenges. He served as Consultant to the U.S. Army Surgeon General on Hematology and Oncology, as Co-Chairman of the NATO Blood Panel and as a contributor to the NATO Prehospital Care Improvement Initiative. He is a Professor of Medicine at the Uniformed Services University. As Board Director, Colonel Cap, Ret., will develop existing and new relationships and military projects in the field of spray dried plasma production and novel blood technologies.

Colonel Cap, Ret., earned a BA cum laude from Harvard University and an MS in Technology and Policy from MIT, and worked in management and policy consulting before attending medical school. He earned an MD magna cum laude and a PhD in Pathology from the Boston University School of Medicine, where he was also elected to the Alpha Omega Alpha Honor Medical Society. He completed residency in Internal Medicine and fellowship in Hematology and Medical Oncology at Walter Reed Army Medical Center, and training in hematopoietic stem cell transplantation at NIH.

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RESEARCH INSTITUTE DIRECTORS

Philip C. Spinella, MD, FCCM

Andrew P. Cap, MD, PhD

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Collaborations

The THOR Network is proud to collaborate with leading institutions and experts worldwide.